When autophagy chaperones liver metabolism.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 25185945.
- Also identified by DOI 10.1016/j.cmet.2014.08.008.
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Abstract
Chaperone-mediated autophagy (CMA) governs degradation of cytosolic proteins damaged by nutritional changes and declines with age. In this issue, Schneider et al. (2014) reveal CMA as a novel player in the regulation of liver lipid and carbohydrate metabolism and suggest that defects in CMA may play a major role in metabolic dysregulation.
Medical subject headings
- Autophagy
- Fatty Liver
- Liver
- Lysosomal-Associated Membrane Protein 2