Cidofovir gel as treatment of follicular spicules in multiple myeloma.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 25188537.
- Also identified by DOI 10.1001/jamadermatol.2014.1616.
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Abstract
The cause of follicular spicules in multiple myeloma (MM) is not known. We present a case of follicular spicules in a patient with MM, which is very reminiscent of trichodysplasia spinulosa caused by a polyomavirus. No trichodysplasia spinulosa-associated polyomavirus could be isolated from the skin lesions; however, the spicules were positive for Merkel cell carcinoma virus, which is also a polyomavirus. Follicular spicules in MM are probably not caused by the trichodysplasia spinulosa-associated virus. Merkel cell polyomavirus could contribute to the origin of this dermatosis.
Medical subject headings
- Carcinoma, Merkel Cell
- Cytosine
- Multiple Myeloma
- Organophosphonates
- Skin Neoplasms