Ch-ch-changes: hormones link stem cell differentiation with metabolic flux.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 25192460.
- Also identified by DOI 10.1016/j.stem.2014.08.006.
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Abstract
Emerging evidence strongly suggests that stem cells and their differentiated progeny display distinct metabolic profiles, but how metabolic changes are coupled with organogenesis has remained unclear. Homem et al. (2014) now reveal a hormone-dependent pathway that couples metabolic changes with stem cell differentiation, thereby terminating neurogenesis in the Drosophila brain.
Medical subject headings
- Cell Proliferation
- Drosophila melanogaster
- Ecdysone
- Neural Stem Cells