Paediatric rheumatic disease: Diagnosing macrophage activation syndrome in systemic JIA.

Vastert, Sebastiaan J; Prakken, Berent J · Nat Rev Rheumatol · 2014

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Abstract

Macrophage activation syndrome (MAS) in systemic juvenile idiopathic arthritis (sJIA) is difficult to distinguish from active sJIA or sepsis. A collaborative effort scoring the performance of different clinical diagnostic criteria provides valuable guidance to clinicians, but challenges in the diagnosis of sJIA-related MAS remain.

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