Brush-like polycarbonates containing dopamine, cations, and PEG providing a broad-spectrum, antibacterial, and antifouling surface via one-step coating.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 25205380.
- Also identified by DOI 10.1002/adma.201402059.
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Abstract
An antibacterial and antifouling surface is obtained by simple one-step immersion of a catheter surface with brush-like polycarbonates containing pendent adhesive dopamine, antifouling polyethylene glycol (PEG), and antibacterial cations. This coating demonstrates excellent antibacterial and antifouling activities against both Gram-positive (S. aureus) and Gram-negative (E. coli) bacteria, proteins, and platelets, good stability under simulated blood-flow conditions, and no toxicity.
Medical subject headings
- Anti-Bacterial Agents
- Catheters
- Cations
- Dopamine
- Polycarboxylate Cement
- Polyethylene Glycols