Super-soft hydrogel particles with tunable elasticity in a microfluidic blood capillary model.

Cui, Jiwei; Björnmalm, Mattias; Liang, Kang; Xu, Chenglong; Best, James P; Zhang, Xuehua; Caruso, Frank · Adv Mater · 2014

basic_science · Level V

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Abstract

Super-soft PEG hydrogel particles with tunable elasticity are prepared via a mesoporous silica templating method. The deformability behavior of these particles, in a microfluidic blood-capillary model, can be tailored to be similar to that of human red blood cells. These results provide a new platform for the design and development of soft hydrogel particles for investigating bio-nano interactions.

Medical subject headings