One-pot synthesis of protein-embedded metal-organic frameworks with enhanced biological activities.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 25211437.
- Also identified by DOI 10.1021/nl5026419.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Protein molecules were directly embedded in metal-organic frameworks (MOFs) by a coprecipitation method. The protein molecules majorly embedded on the surface region of MOFs display high biological activities. As a demonstration of the power of such materials, the resulting Cyt c embedded in ZIF-8 showed a 10-fold increase in peroxidase activity compared to free Cyt c in solution and thus gave convenient, fast, and highly sensitive detection of trace amounts of explosive organic peroxides in solution.
Medical subject headings
- Cytochromes c
- Immobilized Proteins
- Organometallic Compounds
- Peroxides