Polyelectrolyte Films Boost Progenitor Cell Differentiation into Endothelium-like Monolayers.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 25213888.
- Also identified by DOI 10.1002/adma.200702418.
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Abstract
Rapid differentiation of endothelial progenitor cells (EPCs) into confluent mature endothelial cells is important in tissue engineering for the design of autologous, nonthrombotic, vascular grafts. A new method based on EPC culture on poly(sodium-4- styrene-sulfonate)/poly(allylamine hydrochloride), that is, polyelectrolyte-multilayer-coated substrates, reduces the time from two months to two weeks.