Core/Single-Crystal-Shell Nanospheres for Controlled Drug Release via a Magnetically Triggered Rupturing Mechanism.

Hu, Shang-Hsiu; Chen, San-Yuan; Liu, Dean-Mo; Hsiao, Chi-Sheng · Adv Mater · 2008

basic_science · Level V

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Abstract

Core/single-crystal-shell nanospheres are constructed from a poly-(N-vinyl- 2-pyrrolidone) (PVP)-modified silica core with an outer layer of single-crystal iron oxide shell. The nanospheres show outstanding release-and-zero-release characteristics via the addition and removal, respectively, of an external high-frequency magnetic field.