Unpacking the unfolded protein response.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 25215479.
- Also identified by DOI 10.1016/j.cell.2014.08.025.
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Abstract
This year, the Albert Lasker Basic Medical Research Award will be shared by Peter Walter and Kazutoshi Mori for discoveries revealing the molecular mechanism of the unfolded protein response, an intracellular quality control system that detects harmful misfolded proteins in the endoplasmic reticulum and then signals the nucleus to carry out corrective measures.
Medical subject headings
- Awards and Prizes
- Saccharomyces cerevisiae
- Unfolded Protein Response