Metabolism and the other fat: a protocadherin in mitochondria.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 25215484.
- Also identified by DOI 10.1016/j.cell.2014.08.039.
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Abstract
The protocadherin Fat is known as a tumor suppressor regulating growth in Drosophila and for its conserved function during planar cell polarity establishment. McNeill and colleagues now identify an unsuspected role for a C-terminal proteolytic product of Fat in mitochondria: regulating the electron transport machinery and metabolism.
Medical subject headings
- Cadherins
- Cell Adhesion Molecules
- Drosophila Proteins
- Drosophila melanogaster
- Mitochondria