SnapShot: FMRP mRNA targets and diseases.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 25215498.
- Also identified by DOI 10.1016/j.cell.2014.08.035.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
FMRP, or fragile X mental retardation protein is an RNA-binding protein. Mutations in the FMRP protein have been associated with neurological disease as have a number of its mRNA-binding targets. This SnapShot presents 40 bona fide FMRP targets for which mRNA binding and protein regulation have been robustly reported in mammals along with the diseases with which they have been associated.
Medical subject headings
- Brain Diseases
- Fragile X Messenger Ribonucleoprotein 1
- Mental Disorders
- RNA, Messenger