Scalable units for building cardiac tissue.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 25238047.
- Also identified by DOI 10.1002/adma.201403074 and PMC identifier 4245075.
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Abstract
Scalable units for building cardiac tissue are fabricated from biodegradable elastomeric polymers by pairwise stacking of heart-cell scaffolds with sinusoidal internal pore architectures and dedicated perfusable microvessels with rapidly degrading porous interfaces in a parallel flow configuration. This platform supports viable heart cells in vitro and, if validated in vivo, may aid in the regenerative repair of vascularized tissues.
Medical subject headings
- Heart
- Tissue Engineering
- Tissue Scaffolds