Doxorubicin-loaded magnetic silk fibroin nanoparticles for targeted therapy of multidrug-resistant cancer.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 25238148.
- Also identified by DOI 10.1002/adma.201403562.
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Abstract
A strategy to prepare doxorubicin-loaded magnetic silk fibroin nanoparticles is presented. The nanoparticles serve as a nanometer-scale drug-delivery system in the chemotherapy of multidrug-resistant cancer under the guidance of a magnetic field. The magnetic tumor-targeting ability broadens the range of biomedical applications of silk fibroin, and the nanoparticle-assisted preparation strategy is useful for the advancement of other biomacromolecule-based materials.
Medical subject headings
- Antineoplastic Agents
- Doxorubicin
- Drug Delivery Systems
- Fibroins
- Magnets
- Nanoparticles