Gold-nanocrystal-enhanced bioluminescent nanocapsules.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 25243486.
- Also identified by DOI 10.1021/nn504371h.
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Abstract
Metal-enhanced bioluminescence presents a great opportunity to achieve ultrasensitive analysis and imaging with low bioluminescent background and enhanced luminescence. We hereby report metal-enhanced bioluminescence based on bioluminescent protein nanocapsules conjugated with gold nanocrystals. Such gold-nanocapsule complexes exhibit near 10-fold enhancement in bioluminescent intensity and are effectively delivered into the cells with outstanding stability. This work offers a class of bioluminescent nanoparticles for imaging and other applications.
Medical subject headings
- Gold
- Nanoparticles