Molecular recognition of nucleic acids by nucleolipid/dendrimer surface complexes.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 25246334.
- Also identified by DOI 10.1039/c4sm01733a.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
We show for the first time that 1,2-dilauroyl-sn-glycero-3-phosphatidyladenosine nucleolipid surface complexes with cationic poly(amidoamine) dendrimers can be used to selectively bind DNA including oligonucleotides. This molecular recognition has high potential for applications involving biomedical and bioanalytic devices as well as drug delivery systems based on nucleic acids.
Medical subject headings
- DNA
- Dendrimers
- Drug Delivery Systems
- Lipids
- Oligonucleotides
- Polyamines