Protracted fecal shedding of HEV during ribavirin therapy predicts treatment relapse.

Abravanel, Florence; Lhomme, Sébastien; Rostaing, Lionel; Kamar, Nassim; Izopet, Jacques · Clin Infect Dis · 2015

case_series · Level IV

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Abstract

Twenty-four solid-organ-transplant recipients with chronic hepatitis E virus (HEV) infections were given ribavirin therapy for 3 months. All the patients with protracted fecal HEV shedding during treatment suffered a relapse. Monitoring HEV fecal excretion could be used to determine the optimal duration of ribavirin therapy.

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