Muscling up the heart: a preadolescent cardiomyocyte proliferation contributes to heart growth.
Where this comes from
- Record sourced from PubMed, PMID 25258401.
- Also identified by DOI 10.1161/CIRCRESAHA.114.304632 and PMC identifier 4196263.
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Abstract
A recent study from Naqvi et al in <i>Cell</i> shows that in mice during preadolescence, cardiomyocytes undergo a burst of proliferation that is related to a thyroid hormone surge. This study challenges the conventional model of the timing of terminal differentiation and provides a direction for further mechanistic research on cardiomyocyte proliferation and differentiation.
Medical subject headings
- Cell Differentiation
- Cell Proliferation
- Heart
- Myocytes, Cardiac