Deep, dark secrets of melatonin in animal evolution.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 25259913.
- Also identified by DOI 10.1016/j.cell.2014.09.004.
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Abstract
Tosches et al. show that melatonin signaling regulates circadian swimming in annelid worms by rhythmically activating cholinergic neurons. This suggests an evolutionary connection between melatonin signaling in invertebrates and sleep regulation in vertebrates.
Medical subject headings
- Melatonin
- Photoreceptor Cells, Invertebrate
- Polychaeta