Biogenesis of Circular RNAs.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 25259915.
- Also identified by DOI 10.1016/j.cell.2014.09.005.
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Abstract
Circular RNAs are generated during splicing through various mechanisms. Ashwal-Fluss et al. demonstrate that exon circularization and linear splicing compete with each other in a tissue-specific fashion, and Zhang et al. show that exon circularization depends on flanking intronic complementary sequences. Both papers show that several types of circular RNA transcripts can be produced from a single gene.
Medical subject headings
- Drosophila
- RNA
- RNA Precursors
- RNA Splicing
- RNA, Messenger