PINBPA: cytoscape app for network analysis of GWAS data.
Where this comes from
- Record sourced from PubMed, PMID 25260698.
- Also identified by DOI 10.1093/bioinformatics/btu644.
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Abstract
Protein interaction network-based pathway analysis (PINBPA) for genome-wide association studies (GWAS) has been developed as a Cytoscape app, to enable analysis of GWAS data in a network fashion. Users can easily import GWAS summary-level data, draw Manhattan plots, define blocks, prioritize genes with random walk with restart, detect enriched subnetworks and test the significance of subnetworks via a user-friendly interface. PINBPA app is freely available in Cytoscape app store. Supplementary data are available at Bioinformatics online.
Medical subject headings
- Data Mining
- Genome-Wide Association Study
- Protein Interaction Maps
- Software