EasyStrata: evaluation and visualization of stratified genome-wide association meta-analysis data.
other · Level V
Where this comes from
- Record sourced from PubMed, PMID 25260699.
- Also identified by DOI 10.1093/bioinformatics/btu621 and PMC identifier 4287944.
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Abstract
The R package EasyStrata facilitates the evaluation and visualization of stratified genome-wide association meta-analyses (GWAMAs) results. It provides (i) statistical methods to test and account for between-strata difference as a means to tackle gene-strata interaction effects and (ii) extended graphical features tailored for stratified GWAMA results. The software provides further features also suitable for general GWAMAs including functions to annotate, exclude or highlight specific loci in plots or to extract independent subsets of loci from genome-wide datasets. It is freely available and includes a user-friendly scripting interface that simplifies data handling and allows for combining statistical and graphical functions in a flexible fashion. EasyStrata is available for free (under the GNU General Public License v3) from our Web site www.genepi-regensburg.de/easystrata and from the CRAN R package repository cran.r-project.org/web/packages/EasyStrata/. Supplementary data are available at Bioinformatics online.
Medical subject headings
- Computational Biology
- Computer Graphics
- Genome, Human
- Genome-Wide Association Study
- Meta-Analysis as Topic
- Software