Comprehensive analysis of DNA methylation data with RnBeads.
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- Record sourced from PubMed, PMID 25262207.
- Also identified by DOI 10.1038/nmeth.3115 and PMC identifier 4216143.
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Abstract
RnBeads is a software tool for large-scale analysis and interpretation of DNA methylation data, providing a user-friendly analysis workflow that yields detailed hypertext reports (http://rnbeads.mpi-inf.mpg.de/). Supported assays include whole-genome bisulfite sequencing, reduced representation bisulfite sequencing, Infinium microarrays and any other protocol that produces high-resolution DNA methylation data. Notable applications of RnBeads include the analysis of epigenome-wide association studies and epigenetic biomarker discovery in cancer cohorts.
Medical subject headings
- DNA
- DNA Methylation
- Epigenesis, Genetic
- Genome, Human
- Software