Promising cell-based immunotherapy using gamma delta T cells: together is better.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 25278452.
- Also identified by DOI 10.1158/1078-0432.CCR-14-1371.
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Abstract
Gamma delta T-cell response to cellular stress signals expressed by tumor cells makes them promising candidates for cancer immunotherapy. The proof of concept for clinical scale propagation of polyclonal γδ T-cell lines with efficient in vitro and in vivo response against cancer is an important step in this direction.
Medical subject headings
- Cytotoxicity, Immunologic
- Lymphocyte Activation
- Neoplasms
- Neuroblastoma
- Receptors, Antigen, T-Cell, gamma-delta
- T-Cell Antigen Receptor Specificity
- T-Lymphocyte Subsets