Reinventing the neural crest: direct reprogramming makes iNCCs.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 25280213.
- Also identified by DOI 10.1016/j.stem.2014.09.007.
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Abstract
Aberrant neural crest (NC) development is at the origin of many congenital diseases. Given the limitations in human NC cell isolation and expansion, the development of new strategies for NC generation is crucial. In this issue of Cell Stem Cell, Kim et al. (2014) report the direct reprogramming of postnatal fibroblasts into multipotent NC cells.
Medical subject headings
- Cellular Reprogramming
- Multipotent Stem Cells
- Neural Crest
- SOXE Transcription Factors