Wafer-scale fabrication of glass-FEP-glass microfluidic devices for lipid bilayer experiments.
basic_science · Level V
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- Record sourced from PubMed, PMID 25284632.
- Also identified by DOI 10.1039/c4lc00921e.
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Abstract
We report a wafer-scale fabrication process for the production of glass-FEP-glass microdevices using UV-curable adhesive (NOA81) as gluing material, which is applied using a novel "spin & roll" approach. Devices are characterized for the uniformity of the gluing layer, presence of glue in the microchannels, and alignment precision. Experiments on lipid bilayers with electrophysiological recordings using a model pore-forming polypeptide are demonstrated.
Medical subject headings
- Glass
- Lipid Bilayers
- Microfluidic Analytical Techniques
- Polytetrafluoroethylene