Chimera: a Bioconductor package for secondary analysis of fusion products.
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- Record sourced from PubMed, PMID 25286921.
- Also identified by DOI 10.1093/bioinformatics/btu662 and PMC identifier 4253834.
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Abstract
Chimera is a Bioconductor package that organizes, annotates, analyses and validates fusions reported by different fusion detection tools; current implementation can deal with output from bellerophontes, chimeraScan, deFuse, fusionCatcher, FusionFinder, FusionHunter, FusionMap, mapSplice, Rsubread, tophat-fusion and STAR. The core of Chimera is a fusion data structure that can store fusion events detected with any of the aforementioned tools. Fusions are then easily manipulated with standard R functions or through the set of functionalities specifically developed in Chimera with the aim of supporting the user in managing fusions and discriminating false-positive results.
Medical subject headings
- Gene Fusion
- Software