DupliPHY-Web: a web server for DupliPHY and DupliPHY-ML.
other · Level V
Where this comes from
- Record sourced from PubMed, PMID 25294920.
- Also identified by DOI 10.1093/bioinformatics/btu645 and PMC identifier 4308661.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
Gene duplication and loss are important processes in the evolution of gene families. Moreover, growth of families by duplication and retention is an important mechanism by which organisms gain new functions. Therefore the ability to infer the evolutionary histories of families is an important step in understanding the evolution of function. We have recently developed DupliPHY, a software tool to infer gene family histories using parsimony and maximum likelihood. Here, we present DupliPHY-Web a web server for DupliPHY that implements additional maximum likelihood functionality and provides users an intuitive interface to run DupliPHY. DupliPHY-Web is available at www.bioinf.manchester.ac.uk/dupliphy/ : ryan.ames@manchester.ac.uk Supplementary data are available at Bioinformatics online.
Medical subject headings
- Computational Biology
- Evolution, Molecular
- Gene Duplication
- Software