Periostin: a new extracellular regulator of obesity-induced hepatosteatosis.
Level V
Where this comes from
- Record sourced from PubMed, PMID 25295785.
- Also identified by DOI 10.1016/j.cmet.2014.09.005.
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Abstract
Periostin is a crucial extracellular remodeling factor in the inflammatory and tumor microenvironments, but its function in nonalcoholic fatty liver disease remains unclear. Lu et al. (2014) now demonstrate that periostin is a critical player in the regulation of hepatic triglyceride homeostasis and the development of obesity-induced hepatosteatosis.
Medical subject headings
- Cell Adhesion Molecules
- Fatty Liver
- Hypertriglyceridemia
- PPAR alpha