Polymer translocation: the first two decades and the recent diversification.
review · Level V
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- Record sourced from PubMed, PMID 25301107.
- Also identified by DOI 10.1039/c4sm01819b.
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Abstract
Probably no other field of statistical physics at the borderline of soft matter and biological physics has caused such a flurry of papers as polymer translocation since the 1994 landmark paper by Bezrukov, Vodyanoy, and Parsegian and the study of Kasianowicz in 1996. Experiments, simulations, and theoretical approaches are still contributing novel insights to date, while no universal consensus on the statistical understanding of polymer translocation has been reached. We here collect the published results, in particular, the famous-infamous debate on the scaling exponents governing the translocation process. We put these results into perspective and discuss where the field is going. In particular, we argue that the phenomenon of polymer translocation is non-universal and highly sensitive to the exact specifications of the models and experiments used towards its analysis.
Medical subject headings
- Biopolymers
- Cell Membrane
- Membrane Proteins