Novel targets in head and neck cancer: should we be optimistic?
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 25301846.
- Also identified by DOI 10.1158/1078-0432.CCR-14-1776 and PMC identifier 4316824.
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Abstract
Head and neck squamous cell carcinomas have distinct mutation and copy-number profiles depending on human papillomavirus status. Although several challenges remain in biomarker implementation and clinical trial feasibility, incorporating available genomic data will expedite the development of novel therapeutics and predictive biomarker-driven clinical trials. See related article by Seiwert et al., p. 632.
Medical subject headings
- Carcinoma, Squamous Cell
- Genomics
- Head and Neck Neoplasms
- Papillomaviridae
- Papillomavirus Infections
- Tumor Virus Infections