Cellular differences in protein synthesis regulate tissue homeostasis.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 25303523.
- Also identified by DOI 10.1016/j.cell.2014.09.016 and PMC identifier 4222182.
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Abstract
Although sometimes considered a "house-keeping" function, multiple aspects of protein synthesis are regulated differently among somatic cells, including stem cells, and can be modulated in a cell-type-specific manner. These differences are required to establish and maintain differences in cell identity, cell function, tissue homeostasis, and tumor suppression.
Medical subject headings
- Protein Biosynthesis