Malignant melanoma masquerading as an angiofibroma in a patient with MEN-1.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 25317507.
- Also identified by DOI 10.1001/jamadermatol.2014.2186 and PMC identifier 7747011.
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Abstract
Multiple endocrine neoplasia type 1 (MEN-1) is an autosomal dominant syndrome consisting of endocrine tumors of the parathyroid gland, pituitary gland, and pancreas. MEN-1 is caused by loss of function mutations in the <i>MEN1</i> gene, which encodes the tumor suppressor protein menin. Cutaneous collagenomas and facial angiofibromas also have been associated with MEN-1 and may serve as diagnostic clues to the diagnosis. We present a case of amelanotic melanoma resembling a large angiofibroma in a young man with MEN-1.
Medical subject headings
- Angiofibroma
- Melanoma
- Multiple Endocrine Neoplasia Type 1
- Skin Neoplasms