What is the incidence of biliary carcinoma in choledochal cysts, when do they develop, and how should it affect management?
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 25322698.
- Also identified by DOI 10.1007/s00268-014-2831-5.
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Abstract
The incidence of cancer in choledochal cysts (CCs) in adults was calculated to determine the timing and need for surgery. In 78 publications (1996-2010), 434 of 5780 reported CCs patients had cancer. Cholangiocarcinoma (70.4 %) and gallbladder cancer (23.5 %) were the most common malignancies. Only nine malignancies were reported before age 18 (0.42 %). In contrast, the incidence of malignancy in adults was 11.4 %. The median age for diagnosis of cancer was 42 years, and the incidence increased with each decade.
Medical subject headings
- Bile Duct Neoplasms
- Bile Ducts, Intrahepatic
- Cholangiocarcinoma
- Choledochal Cyst
- Gallbladder Neoplasms