Photopatterning of multifunctional hydrogels to direct adult neural precursor cells.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 25323149.
- Also identified by DOI 10.1002/adhm.201400395.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Matrix-metalloproteinase and photosensitive peptide units are combined with heparin and poly(ethylene glycol) into a light-sensitive multicomponent hydrogel material. Localized degradation of the hydrogel matrix allows the creation of defined spatial constraints and adhesive patterning for cells grown in culture. Using this matrix system, it is demonstrated that the degree of confinement determines the fate of neural precursor cells in vitro.
Medical subject headings
- Adult Stem Cells
- Hydrogels
- Light
- Neural Stem Cells