Immunological responses triggered by photothermal therapy with carbon nanotubes in combination with anti-CTLA-4 therapy to inhibit cancer metastasis.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 25331930.
- Also identified by DOI 10.1002/adma.201402996.
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Abstract
Photothermal ablation of primary tumors with single-walled carbon nanotubes is demonstrated to be able to trigger significant adaptive immune responses, which are not observed if tumors are removed by surgical resection. Such a treatment in combination with anti-CTLA-4 antibody therapy is able to prevent the development of tumor metastasis, which is a major cause of cancer death.
Medical subject headings
- Antibodies
- CTLA-4 Antigen
- Nanotubes, Carbon