Microbicides and their potential as a catalyst for multipurpose sexual and reproductive health technologies.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 25335841.
- Also identified by DOI 10.1111/1471-0528.12843 and PMC identifier 4206831.
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Abstract
There is an urgent need for technologies to prevent sexual acquisition of HIV infection in young women in sub-Saharan Africa. After two decades of 11 pivotal trials of seven products, anti-retroviral-based topical microbicides are showing promise. Building on the CAPRISA 004 trial findings, several trials of new anti-viral agents, novel delivery mechanisms and combination/multipurpose products that address challenges of adherence and meet the sexual and reproductive health needs of men and women, including preventing HIV infection, are underway.
Medical subject headings
- Adenine
- Anti-HIV Agents
- Anti-Infective Agents
- HIV Infections
- Organophosphonates