A role for interleukin-22 in the alleviation of metabolic syndrome.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 25362255.
- Also identified by DOI 10.1038/nm.3748.
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Abstract
Increasing evidence points to a role for the immune system in the regulation of metabolism. Two new studies in mice indicate treatment with interleukin-22 restores mucosal immunity in diabetes and alleviates metabolic disease, resulting in improved glycemic control.
Medical subject headings
- Blood Glucose
- Cytokines
- Diabetes Mellitus, Type 2
- Endoplasmic Reticulum Stress
- Gene Expression Regulation
- Insulin
- Insulin-Secreting Cells