Smart nanocarrier: self-assembly of bacteria-like vesicles with photoswitchable cilia.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 25363552.
- Also identified by DOI 10.1021/nn5042366.
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Abstract
Bioinspired cell deformation aids in the design of smart functional molecular self-assemblies. We report on a system of bacteria-like vesicles which release entrapped drug upon developing hairs triggered by UV irradiation, just like cilia stretching from the surface of bacteria. The formation of cilia leads to a less intact membrane, which allows release of entrapped drug. This bioinspired design created a smart nanocarrier that releases the payload via deformation rather than complete breaking.
Medical subject headings
- Bacteria
- Cilia
- Nanostructures
- Ultraviolet Rays