Hybrid ZnO nanorod-polymer brush hierarchically nanostructured substrate for sensitive antibody microarrays.

Hu, Weihua; Liu, Yingshuai; Chen, Tao; Liu, Yang; Li, Chang Ming · Adv Mater · 2015

other · Level V

Where this comes from

Abstract

A hierarchically nanostructured organic-inorganic hybrid substrate comprising randomly oriented ZnO nanorods on glass slide with coaxially tethered dense polymer brush, POEGMA-co-GMA is reported for highly sensitive antibody microassay, achieving excellent detection specificity, and superior detection limit of as low as 100 fg mL(-1) for biomarkers in human serum within a 1 h assay time.

Medical subject headings