Perylene-diimide-based nanoparticles as highly efficient photoacoustic agents for deep brain tumor imaging in living mice.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 25376906.
- Also identified by DOI 10.1002/adma.201402972 and PMC identifier 4347809.
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Abstract
In order to promote preclinical and clinical applications of photoacoustic imaging, novel photoacoustic contrast agents are highly desired for molecular imaging of diseases, especially for deep tumor imaging. Here, perylene-3,4,9,10-tetracarboxylic diiimide-based near-infrared-absorptive organic nanoparticles are reported as an efficient agent for photoacoustic imaging of deep brain tumors in living mice with enhanced permeability and retention effect.
Medical subject headings
- Brain Neoplasms
- Diagnostic Imaging
- Imides
- Nanoparticles
- Perylene
- Photoacoustic Techniques