pH-stimulated DNA hydrogels exhibiting shape-memory properties.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 25377247.
- Also identified by DOI 10.1002/adma.201403702.
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Abstract
Nucleic acid-functionalized polyacrylamide chains that are cooperatively cross-linked by i-motif and nucleic acid duplex units yield, at pH 5.0, DNA hydrogels exhibiting shape-memory properties. Separation of the i-motif units at pH 8.0 dissolves the hydrogel into a quasi-liquid phase. The residual duplex units provide, however, a memory code in the quasi-liquid allowing the regeneration of the hydrogel shape at pH 5.0.
Medical subject headings
- DNA
- Hydrogels