Structurally Controlled Bio-hybrid Materials Based on Unidirectional Association of Anisotropic Microparticles with Human Endothelial Cells.

Yoshida, Mutsumi; Roh, Kyung-Ho; Mandal, Suparna; Bhaskar, Srijanani; Lim, Dongwoo; Nandivada, Himabindu; Deng, Xiaopei; Lahann, Joerg · Adv Mater · 2009

basic_science · Level V

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Abstract

Biocompatible anisotropic polymer particles with bipolar affinity towards human endothelial cells are a novel type of building blocks for microstructured bio-hybrid materials. Functional polarity due to two biologically distinct hemispheres has been achieved by synthesis of anisotropic particles via electro-hydrodynamic co-jetting of two different polymer solutions and subsequent selective surface modification.