Multifunctional "smart" particles engineered from live immunocytes: toward capture and release of cancer cells.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 25382706.
- Also identified by DOI 10.1002/adma.201402213.
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Abstract
Multifunctional "smart" particles with magnetic, topographic, cell-targeting, and stimulus-responsive properties are obtained using a "live template" strategy. These particles exhibit improved efficiency in capture of target cancer cells by introducing synergistic topographic interactions, and enable the release of captured cells with high viability via reduction of disulfide bonds. Diverse multifunctional particles can be designed using the "live template" strategy.
Medical subject headings
- Biomimetic Materials
- Cell Engineering
- Macrophages
- Neoplasms