Cholesterol metabolism and immunity.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 25390746.
- Also identified by DOI 10.1056/NEJMcibr1412016.
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Abstract
A study in mice implicates a cholesterol derivative in damping down the inflammatory response mediated by interleukin-1β and explaining, at least in part, the immunosuppressive effect of type I interferon, which is used in the treatment of multiple sclerosis.
Medical subject headings
- Hydroxycholesterols
- Inflammation
- Interleukin-1beta
- Steroid Hydroxylases