Orthopaedic manifestations and treatment outcome of two siblings with Escobar syndrome and homozygous mutations in the CHRNG gene.

Sung, Ki Hyuk; Lee, Sang-Heon; Kim, Namshin; Cho, Tae-Joon · J Pediatr Orthop B · 2015

case_report · Level V

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Abstract

Escobar syndrome is a nonlethal subtype of multiple pterygium syndromes, characterized by webbing across the joints, congenital joint contracture, facial dysmorphism and a variety of other congenital anomalies. We report orthopaedic manifestation and the treatment outcome of two siblings with Escobar syndrome caused by homozygous mutations of the CHRNG gene.

Medical subject headings