A deeper look into translation initiation.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 25417100.
- Also identified by DOI 10.1016/j.cell.2014.10.005.
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Abstract
Eukaryotic translation initiation requires coordinated assembly of a remarkable array of initiation factors onto the small ribosomal subunit to select an appropriate mRNA start codon. Studies from Erzberger et al. and Hussain et al. bring new insights into this mechanism by looking at early and late initiation intermediates.
Medical subject headings
- Eukaryotic Initiation Factor-1
- Eukaryotic Initiation Factor-3
- Eukaryotic Initiation Factors
- Kluyveromyces
- Peptide Chain Initiation, Translational
- Ribosome Subunits, Small, Eukaryotic
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins