Inflammation versus host defense in obesity.
other · Level V
Where this comes from
- Record sourced from PubMed, PMID 25440053.
- Also identified by DOI 10.1016/j.cmet.2014.10.013 and PMC identifier 4755485.
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Abstract
Obesity is characterized by a state of low-grade, chronic inflammation. Wang et al. (2014) report that immune cells from obese mice have decreased production of IL-22, a cytokine involved in immune responses and inflammation, and reveal therapeutic effects of exogenous IL-22 against obesity-linked metabolic dysfunctions.
Medical subject headings
- Diabetes Mellitus
- Immunity, Mucosal
- Interleukins
- Metabolic Diseases