Increased plasma incretin concentrations identifies a subset of patients with persistent congenital hyperinsulinism without KATP channel gene defects.
case_series · Level IV
Where this comes from
- Record sourced from PubMed, PMID 25444530.
- Also identified by DOI 10.1016/j.jpeds.2014.09.019.
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Abstract
Congenital hyperinsulinism causes profound hypoglycemia, which may persist or resolve spontaneously. Among 13 children with congenital hyperinsulinism, elevated incretin hormone concentrations were detected in 2 with atypical, persistent disease. We suggest that incretin biomarkers may identify these patients, and that elevated hormone levels may contribute to their pathophysiology.
Medical subject headings
- Biomarkers
- Congenital Hyperinsulinism
- Incretins
- KATP Channels