Microencapsulation of indocyanine green for potential applications in image-guided drug delivery.

Zhu, Zhiqiang; Si, Ting; Xu, Ronald X · Lab Chip · 2015

basic_science · Level V

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Abstract

We present a novel process to encapsulate indocyanine green (ICG) in liposomal droplets at high concentration for potential applications in image-guided drug delivery. The microencapsulation process follows two consecutive steps of droplet formation by liquid-driven coaxial flow focusing (LDCFF) and solvent removal by oil phase dewetting. These biocompatible lipid vesicles may have important applications in drug delivery and fluorescence imaging.

Medical subject headings